Composition
Each ml contains:
Tinctures (f) of
Fresh organic Echinacea herb (Echinacea purpurea) 860 mg/ml 0.949 ml
Fresh organic Echinacea root (Echinacea purpurea) 45 mg/ml 0.050 ml
1 ml = 33 drops
Alcohol content: 67% v/v
Dosage
Adults: Prevention: 20 drops in a
small amount of water, once a day, before breakfast. Use daily for a maximum of
3 months or, on longer periods, for 3 weeks per month. Salivate before
swallowing.
Treatment: 20-30 drops in a small amount of water, 3-5 times daily, until
symptoms stop. For an optimal efficacy, begin the treatment with the maximum
dose (30 drops, 5 times daily) as soon as the first symptoms appear.
Children: Prevention: 1-2 drops for each year of age, once a day.
Treatment: 1-2 drops for each year of age, 3-5 times daily.
For children, mix Echinaforce® Liquid in a small amount of juice. For very young
children, let the diluted Echinaforce® Liquid rest for a few minutes to allow
alcohol to evaporate.
Historical overview
Long before the coming of the European
settlers, the native Americans used Echinacea (also called Purple Cone Flower)
to treat a variety of problems, from infections to snake bites. In the United
States, Echinacea was popularized by the eclectic physicians` movement in the
19th Century.After that, its use was almost forgotten until the 1980`s. In
Europe, however, Echinacea was popular with the medical world from the beginning
of the Century and has been the subject of numerous clinical studies. Today,
Echinacea is the most widely sold medicinal herb in the world.
Actions and pharmacology
In vitro studies have revealed Echinacea's action mechanism: its
polysaccharides and polyacetylenes fractions stimulate the phagocytosis of
macrophages and the production of cytokines like interleukine-1,
interleukine-6 (also called interferon beta), interleukine-10 and TNF alpha
factor. This effect shows Echinacea's ability to stimulate the immune system
in cases of infection.(1)
Chicoric acid and analogues derived from caffeic acid are presently under
investigation for their effect on HIV-1 replication.(2)
Echinacea, particularly the echinacosides and caffeic acid derivatives,
might protect collagen structures against degradation (oxidation) caused by
free radicals. This antioxidant effect is also useful in reducing skin
damage caused by sun exposure. The combination of Echinacea's antioxidant
and immuno-stimulant effects might explain its healing virtues in topical
applications.(3)
Scientific studies
Many clinical studies demonstrate echinacea's efficacy as an immune system
stimulant.(4-6) According to the authors of an important meta-analysis (a
review of articles on clinical studies), Echinacea Liquid is effective
against respiratory infections, especially if taken as soon as the first
symptoms appear.(7)
Echinaforce® Liquid has also been the subject of conclusive clinical
studies:
A survey of Echinaforce® Liquid effectiveness was conducted from September
1989 to April 1990. The authors conclude: " Echinaforce's efficacy was
judged clinically significant by 88.2% of patients on themselves and by
86.8% of their attending physicians ".(8)
In a double-blind study conducted in Sweden on 119 patients (55 patients
took 6 tablets of Echinaforce® Liquid daily and 64 took a placebo), the
researchers conclude that, after an 8 day trial, 78% of patients found
Echinaforce® Liquid to be more effective than the placebo.(9)
Precautions,
contraindications and interactions
Contraindication: known allergy to one of the ingredients or to any flower
belonging to the daisy (asteracea) family.
A few cases of prolonged bleeding time were reported. It is therefore not
recommended to combine echinacea with anticoagulant medications like
Coumadin®.
Echinacea is an immune stimulant, therefore its combination with
immuno-suppressive medications like Methotrexate® or Immuran® is
contraindicated. Echinacea is also not recommended for people suffering from
leukemia or other auto-immune diseases.
A study conducted in Toronto by the Motherisk Program states that Echinacea
is safe during pregnancy. (10) However, it is always best to consult a
competent health professional.
Therapeutic combinations
FLUS and COLDS
Echinacea Lozenges, Usneasan, Drosinula®, Santasapina® Syrup and Lozenges,
Resistasan®, Pulsaralia, Sinna, Arasma
COUGHS
Usneasan, Drosinula®, Santasapina®, Arasma, Resistasan®
WOUNDS
Comfrey, Tormentavena®, Molkosan®, Bioforce Cream, Echinacea Cream,
Symphytum Cream
IMPETIGO
As supportive therapy: Molkosan® (diluted, topical), Echinacea Cream
CYSTITIS
Cystoforce, Golden Rod
References:
1. Burger Ra, Torres AR, Warren RP et al. Echinacea-induced cytokine by
human macrophages. Int J Immunopharmacol 1997;19(7):371-9.
2. Lin Z, Neamati N, Zhao H et al. Chicoric acid analogues as HIV-1
integrase inhibitors. J Med Chem 1999;42(8):1401-14.
3. Facino RM, Carini M, Aldini G et al. Echinacoside and caffeoyl conjugates
protect collagen from free radical-induced degradation: a potential use of
Echinacea extracts in the prevention of skin photodamage. Planta Med
1995;61(6):510-4.
4. Gunning K. Echinacea in the treatment and prevention of upper respiratory
tract infections. West J Med 1999;171:198-200.
5. Barrett B, Vohmann M, Calabrese C. Echinacea for upper respiratory
infection. J Fam Pract 1999;48:628-35.
6. Grimm W, Muller HH. A randomized controlled trial of the effect of fluid
extract of Echinacea purpurea on the incidence and severity of colds and
respiratory infections. Am J Med 1999;106:138-43.
7. Barrett B, Vohmann M et Calabrese C. Echinacea for Upper respiratory
infections. J Fam Pract 1999;48(8):628-35.
8. Degenring FH, Enquête sur l'efficacité thérapeutique d'Echinaforce®.
Ganzheits Medizin 1995;2:88-94.
9. Brinkeborn R, Shah D, Geissbühler S et al. Echinaforce® dans le
traitement des états grippaux aigus. Ganzheits Medizin 1998;10(1):26-29.
10. Gallo M, Sarkar M, Au W et al. Pregnancy outcome following gestational
exposure to echinacea: a prospective controlled study. Arch Intern Med
1999;160(20):3141-3.
The
statements have not been evaluated by the Food and Drug Administration.
This product is not meant to diagnose, treat, cure or prevent any disease.
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